ICARE Newsletter Fall 2023

BRCA1 and BRCA2 Carriers: Cancer Risks with Oral Contraceptive Use (UK)

Among female BRCA1 and BRCA2 carriers, a recent study found that oral contraceptive use is associated with:
› Raised risk of breast cancer, but only in those using for over 5 years (relative risk: 1.25)
› Lower risk of ovarian cancer (nearly cut in half)

Park, et al. Carcinogenesis. 2022;43(3):231-242. PMID:

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