In a recently published study based on the VA’s Million Veteran Program, men with the HOXB13 p.G84E variant (the common variant in European populations, upon which much of the data is based) had a higher risk of prostate cancer, a slightly earlier age at diagnosis, and did not tend to develop more aggressive disease.
Crawford, et al. J Natl Compr Canc Netw. 2025;23(10):e257055. PMID: 40953603.
Article available at: https://pubmed.ncbi.nlm.nih.gov/40953603/.
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