A new study, which included ICARE participants, found that BRCA1/2 carriers with ovarian cancer have a relatively LOW risk of breast cancer.
The hazard ratio for breast cancer after ovarian cancer compared to no ovarian cancer was 0.18 (95% CI: 0.12-0.27; P<0.0001). This means that getting breast cancer after already having ovarian cancer was MUCH less common.
Why is this important?
- This means that BRCA carriers have a relatively low risk of breast cancer after ovarian cancer
- Therefore, risk-reducing mastectomy may not routinely recommended, but may be an option for long term survivors
- Breast screening is reasonable through breast MRI and mammograms
Learn more by reading the article at: https://pubmed.ncbi.nlm.nih.gov/41762747/
Reference: Apostol et al. J Clin Oncol. 2026:JCO2501648. PMID: 41762747.
Through ICARE, we aspire to share cancer-related information that may be of interest. If you have questions or clarifications, please direct them to your healthcare provider.
