ICARE Social Media Post August 2025

Von Hippel-Lindau (VHL)-related tumors and Belzutifan treatment

A new study presented at the American Society of Clinical Oncology (ASCO) annual meeting showed that Belzutifan treatment of VHL-related tumors durably shrinks tumors and may reduce the number of surgeries needed in patients with cancers associated with a von Hippel-Lindau (VHL) gene deletion or mutation.

Five-year follow-up findings showed the following response rates:

  • Renal cell cancer: 70%
  • Hemangioblastomas of the CNS: 50%
  • Pancreatic neuroendocrine tumors (PNET): 90%

Learn more by reading the Renal & Urology News article: https://www.renalandurologynews.com/reports/cancer-belzutifan-durable-response-von-hippel-lindau-treatment-risk/

Reference: Sakhnovsky. Renal & Urology News. Belzutifan Provides Durable Response in Von Hippel Lindau-Related Cancers Such as RCC.

Permanent link to this article: https://inheritedcancer.net/post080525/