ICARE Social Media Post November 2025

CHEK2: How much does breast cancer family history and non-genetic risk factors affect risk?

A new study looked at breast cancer risks in CHEK2 carriers based on family history and found that risks for breast cancer were much higher in those with a family history and additional non-genetic risk factors further modified risks.

To learn more read the article at: https://jamanetwork.com/journals/jamaoncology/article-abstract/2839917

Reference: O’Brien, et al. JAMA Oncol. 2025. Online ahead of print. PMID: 41066089.

Permanent link to this article: https://inheritedcancer.net/post11192025/