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ICARE Newsletter Summer 2019

New Information About Cancer Risks for Inherited Cancer Genes: DICER1

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In a study of over 100 individuals with a DICER1 mutation, findings suggest that 5.3% of individuals had developed cancer by age 10, and 19.3% by age 50. After age 10, cancer risks for women were higher compared to men. Specific cancers for which risks were high included gynecologic and thyroid cancers. These findings are important to characterize cancers and natural history of the condition among those with DICER1 mutations, which is tremendously important for genetic counseling, risk counseling, and follow-up care.

Stewart, et al. J Clin Oncol. 2019 March. PMID: 30715996.

Permanent link to this article: https://inheritedcancer.net/8nls2019/