A new study in which ICARE participants were included reported that compared to 1.5% in the general population, the risk of melanoma may be slightly elevated: in BRCA1/2 carriers:
○ BRCA1: 2.5%
○ BRCA2: 2.3%
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Reference: Narod et al. Hered Cancer Clin Pract. 2024;22(1):7. PMID: 38741145.