Our team’s newly published study among young Black women with triple-negative breast cancer (TNBC) found that:
- Those in the “high” West African ancestry group had more luminal androgen receptor tumors and less mesenchymal tumors than those in the “low” West African ancestry group (14.9% vs. 4.9%; 25.5% vs. 34.2%).
- Mesenchymal tumors were marginally associated with worse overall survival (although it did not reach statistical significance).
These findings underscore how TNBC subtypes may be used as prognostic biomarkers across populations.
Read the full article here: https://www.nature.com/articles/s41523-025-00731-0
Reference: Rajagopal, et al. npj Breast Cancer 11, 28 (2025). https://doi.org/10.1038/s41523-025-00731-0