ICARE Social Media Post July 2025

BRCA1/2 Carriers with Breast Cancer: Removal of Ovaries and Fallopian Tubes Lowers Risk of Death

A new study among BRCA1/2 carriers with breast cancer showed that the overall risk of death was 48% lower for those that removed their ovaries and fallopian tubes. Specifically, these women had lower risks of:

  • all-cause mortality
  • breast cancer-specific mortality
  • second non-breast cancer development

What about other health risks that can happen when ovaries are removed (causing menopause)?

  • Study results showed that benefits were seen without a higher risk of other adverse long-term health outcomes, such as heart diseases

Why is this important?

  • This information may give women with breast cancer added information about the health benefits of removing their ovaries; and reassure them about other possible health-related side effects

Learn more by reading the full article at: https://www.thelancet.com/journals/lanonc/article/PIIS1470-2045(25)00156-1/fulltext

Reference: Hassan, et al. Lancet Oncol. 2025;26(6):771:780. PMID: 40347974.

Permanent link to this article: https://inheritedcancer.net/post072225/