ICARE Newsletter Fall 2025

Ovarian Cancer: 1 in 4 Cases Could Have Been Prevented!

A new study of 1877 ovarian cancer patients showed almost 25% of patients had ‘missed opportunities’ for salpingectomy (removal of fallopian tubes) when they had another surgery or procedure before their ovarian cancer diagnosis. Additionally, 6% of patients had a close relative  with  ovarian  cancer, and  almost  20% had  a mutation  in  an

ovarian cancer gene, only found after an ovarian cancer diagnosis. Most common genes were BRCA1 and BRCA2, followed by ATM, BRIP1, MLH1/MSH2, PALB2, RAD51C, and RAD51D. This study shows the importance of preventing ovarian cancer, and how genetic testing and preventive care can lower risks. Ultimately, we as a community must try harder to find women at high risk, and offer them genetic testing, before they get ovarian cancer.

Moufarrjj, et al. JAMA Surg. 2025:e252810. PMID: 40802262. Article available at: https://pubmed.ncbi.nlm.nih.gov/40802262/. Social media post available at: https://www.facebook.com/share/p/1MLT9n2Psi/

Permanent link to this article: https://inheritedcancer.net/nlf20253/