ICARE Social Media Post March 2026

BRCA1/2: Preventive Mastectomy vs. Screening

A new study shows similar rates of death from breast cancer when comparing 460 women who had a mastectomy with 745 women who chose surveillance (screening).

Why is this important?

  • For women choosing surveillance, these results are reassuring that survival is not likely to be compromised.
  • As expected, breast cancer incidence is greatly lowered in the mastectomy group compared to the surveillance group. Specifically, mastectomy lowered breast cancer risk by 94% with a 2% rate of occult cancer after mastectomy.

Learn more at: https://ascopubs.org/doi/10.1200/JCO-25-00834

Reference: Gandhi, et al. J Clin Oncol. 2026:JCO2500834. PMID: 41637687.

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