Newsletter Fall 2021

Breast Cancer Risks Remain High in PALB2 & BRCA

A new study found that lifetime breast cancer risk is 15% or more in female BRCA1, BRCA2, and PALB2 carriers over age 65. This level of risk warrants consideration for continuing breast MRI.1 These results are similar to those of a study that included ICARE participants,2 which reported the risk of developing breast cancer remains high after age 60 in both BRCA1 and BRCA2 carriers, supporting continued cancer screening in older mutation carriers.

1Boddicker, et al. J Clin Oncol. 2021 Jul. PMID: 34292776. 2Stjepanovic, et al. Breast Cancer Res Treat. 2021 Jun. PMID: 33423179.

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