The National Comprehensive Cancer Network (NCCN) just released updated Genetic/Familial High-Risk Assessment: Colorectal, Endometrial, Gastric Cancer guidelines on June 13th, 2025 (Version 1.2025). There are many updates found in these new guidelines including updates to MSH2, EPCAM, PMS2, CDH1, NTHL1, and TP53 content as well as updates to the clinical diagnostic criteria for Peutz-Jeghers Syndrome.
To read more, check out the full guidelines by creating a FREE account at:
https://www.nccn.org/professionals/physician_gls/pdf/genetics_ceg.pdf
