ICARE Social Media Post October 2023

What Are Established Cancer Genes?

There are many different inherited breast cancer genes, and different genes lead to different levels of breast cancer risk:

  • Some genes lead to high risks, defined as more than 4-fold risk of developing breast cancer: BRCA1, BRCA2, PALB2, TP53, PTEN, CDH1.
  • While other lead to less high risks, in the range of 2-4 fold risk: CHEK2, ATM, BARD1, RAD51C, RAD51D.

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