As featured in our Fall 2023 newsletter, inherited T790M EGFR mutations lead to a higher risk of lung cancer and are more common in the Southeast United States due to a ‘founder effect’. A study, in which our fellow Vanderbilt colleagues contributed, among individuals with this inherited cancer gene mutation found that more than half of the participants were affected with lung cancer. These findings highlight the importance of identifying individuals with this mutation to investigate CT-based lung cancer screening among these high-risk individuals. Knowledge is power! 💡
Learn more at: https://pubmed.ncbi.nlm.nih.gov/37579253/
Reference: Oxnard, et al. J Clin Oncol. 2023;41(34):5274-5284. PMID: 37579253.