A new study evaluated 23 hereditary cancer genes and found 19 new gene associations, including 7 new associations with cancer and 12 new associations with non-neoplastic diseases. Specifically, the below genes were found to have an increased risk of disease:
APC: benign liver/bile duct tumors, gastritis, and duodenitis
ATM: stomach cancer and pancreatic cancer
BRCA1/2: ovarian cysts
CHEK2: leukemia and plasma cell cancers
MEN1: acute pancreatitis
MSH6: bladder cancer
MUTYH (biallelic): kidney cancer
PTEN: chronic gastritis
Check out the full article to learn more at 👇
https://jamanetwork.com/journals/jamaoncology/fullarticle/2791551
Reference: Zeng, et al. JAMA Oncol. 2022 April. doi:10.1001/jamaoncol.2022.0373. PMID: 35446370.