ICARE Social Media Post August 2023

  BRCA1/2 Outcomes: Metastatic Breast Cancer  

According to a recent study, germline BRCA1/2 status did not affect prognosis. However, outcomes differed by immunohistochemistry (IHC) subtype as follows:

  • Triple negative disease: overall and progression free survival was better than expected (compared to BRCA negative patients)
  • Hormone receptor+/HER-: progression free survival was lower than expected (compared to BRCA negative patients)

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Reference: Mailliez, et al. Int J Cancer. 2023;152(5):921-931. PMID: 36161271.

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