ICARE Social Media Post September 2020

NCCN Genetic Testing Choice Updates

The National Comprehensive Cancer Network (NCCN) released new guidelines on September 8th, 2020, which included updates to genetic testing choices and considerations as follows:
  • Choice of multi-gene panel may be guided by genes included, analyses offered, and financial assistance programs available for family testing
  • Significant limitations in interpretations of polygenic risk scores: 
  • NOT recommended for use in clinical management; however, if being considered for use to guide clinical management, interpret and discuss in the context of Genetic Counseling/Results interpretation
  • Recommend use in context of clinical trial
  • VUS testing for family members should NOT be done for clinical purposes unless data exist to support discrepancy in results interpretation
You can check out the full guidelines by creating a FREE account at: https://www.nccn.org/professionals/physician_gls/pdf/genetics_bop.pdf 

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