Tag: Hereditary Mixed Polyposis Syndrome

ICARE Social Media Post September 2020

GREM1 Duplication

The GREM1 gene leads to hereditary mixed polyposis syndrome, characterized by multiple polyps of mixed pathology and high risks for colorectal cancer.   A specific duplication in the 5′ regulatory region of the GREM1 gene has been found in a subset of Ashkenazi Jewish individuals with hereditary mixed polyposis syndrome; therefore, GREM1 genetic testing is …

Continue reading

Permanent link to this article: https://inheritedcancer.net/post90420/