Tag: Leukemia

ICARE Featured Video July 2025

Myelodysplastic Syndrome (MDS) and Acute Myeloid Leukemia (AML) Following PARP Inhibitor Therapy

Below is a featured video from the July 2025 case conference, during which Elizabeth Swisher, MD from the University of Washington discusses Myelodysplastic Syndrome (MDS) and Acute Myeloid Leukemia (AML) following PARP inhibitor therapy.

Permanent link to this article: https://inheritedcancer.net/video71025/

ICARE Newsletter Fall 2022 

 Inherited Cancer Genes: New Associations 

A new study led by colleagues at Vanderbilt University Medical Center, including our clinical geneticist colleague, Dr. Georgia Wiesner, evaluated 23 hereditary cancer genes and found 19 new gene associations including 7 new associations with cancer and 12 new associations with noncancer diseases. The associations with cancer versus other conditions is included in the table. …

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Permanent link to this article: https://inheritedcancer.net/icare-newsletter-fall-2022-inherited-cancer-genes-new-associations/

ICARE Social Media Post June 2022

New Variants Linked to Hereditary Cancer

A new study evaluated 23 hereditary cancer genes and found 19 new gene associations, including 7 new associations with cancer and 12 new associations with non-neoplastic diseases. Specifically, the below genes were found to have an increased risk of disease:APC: benign liver/bile duct tumors, gastritis, and duodenitisATM: stomach cancer and pancreatic cancerBRCA1/2: ovarian cystsCHEK2: leukemia …

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Permanent link to this article: https://inheritedcancer.net/post60122/

ICARE Newsletter Summer 2018

Inherited Leukemias: The Importance of TP53/Li-Fraumeni Syndrome and Other Genes

It has long been established that the risk for developing leukemia in childhood is high among individuals with Li-Fraumeni Syndrome; however, better understanding the characteristics of leukemia among these individuals is important to guide treatment approaches. In a study of children with Acute Lymphocytic Leukemia (ALL), those with a germline TP53 mutation (compared to those …

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Permanent link to this article: https://inheritedcancer.net/11nls2018/