The panel set a specific minimal set of genes to test for colorectal, endometrial, and gastric cancer: COLORECTAL CANCER GENES(including genes that predispose to polyps) Additional genes that sometimes get included: ATM, BLM, CHEK2, GALNT12, RNF43, and RPS20. ENDOMETRIAL (UTERINE) CANCER GENES GASTRIC CANCER GENES Test selection and decision to retest including additional genes beyond these …
Tag: Urothelial Cancer
Permanent link to this article: https://inheritedcancer.net/nlf20262/
ICARE Social Media Post December 2020
Broader Germline Testing for Urothelial Cancer
ICARE Social Media Post December 2020
Broader Germline Testing for Urothelial Cancer
The most common inherited form of urothelial cancers is Lynch Syndrome. However, a study showed that of 586 individuals with urothelial cancer, 80 had a mutation in an inherited cancer gene (14%). Mutations in several genes were observed; however, πππ2 and π½ππΎπΌ2 were both significantly associated with urothelial cancer (odds ratio of 3.7). Confirmatory …
Permanent link to this article: https://inheritedcancer.net/post120420/
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