The most common inherited form of urothelial cancers is Lynch Syndrome. However, a study showed that of 586 individuals with urothelial cancer, 80 had a mutation in an inherited cancer gene (14%). Mutations in several genes were observed; however, πππ2 and π½ππΎπΌ2 were both significantly associated with urothelial cancer (odds ratio of 3.7). Confirmatory …
