ICARE Newsletter Fall 2025

BRCA1/2 Carriers: High Risk of Breast Implant-Associated Lymphoma

In a new study of female BRCA1/2 carriers who had breast cancer, there was a 16-fold higher risk of anaplastic large-cell lymphoma associated with breast implants. This occurred in BRCA1/2 carriers who received textured breast implants as part of breast reconstruction. This is important information for BRCA1/2 carriers to know about to guide breast reconstruction options, including:

  1. those thinking about breast reconstruction options
  2. those who already had reconstruction and have textured implants in place.

Ghione, et al. Blood Advl. 2025;9(17):4436-4443. PMID: 40512039. Article available at: https://pubmed.ncbi.nlm.nih.gov/40512039/. Social media post available at: https://www.facebook.com/share/p/17JP5qxFrx/

Permanent link to this article: https://inheritedcancer.net/nlf20254/