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There are many different inherited breast cancer genes, and different genes lead to different levels of breast cancer risk:
- Some genes lead to high risks, defined as more than 4-fold risk of developing breast cancer: BRCA1, BRCA2, PALB2, TP53, PTEN, CDH1.
- While other lead to less high risks, in the range of 2-4 fold risk: CHEK2, ATM, BARD1, RAD51C, RAD51D.