ICARE Social Media Post June 2023

Updates to NCCN Guidelines: Genetic/Familial High-Risk Assessment: Colorectal Version 1.2023

The National Comprehensive Cancer Network (NCCN) just released updated colorectal cancer guidelines which includes:

  • at a minimum the following colorectal cancer genes should be included on multi-gene panel testing: APC, MUTYH, MLH1, MSH2, MSH6, PMS2, EPCAM, BMPR1A, SMAD4, PTEN, STK11, & TP53
  • NTHL1 tumor syndrome recommendation revisions, including modification of breast cancer risks and recommendation of baseline upper endoscopy beginning at age 30-35
  • addition of MBD4-associated neoplasia syndrome

You can check out the full guidelines by creating a FREE account at: https://www.nccn.org/professionals/physician_gls/pdf/genetics_colon.pdf

Permanent link to this article: https://inheritedcancer.net/post60823/