Among 4,500 post-menopausal women with breast cancer, 3.55% had a mutation in a gene associated with inherited breast cancer (3-fold higher than what was seen among women who were cancer-free).
BRCA1/2 mutations were seen more frequently in women diagnosed with breast cancer at or below age 65 (2.21%) compared to those diagnosed after age 65 (1.09%).
This study provides additional information to take into consideration when refining national practice guidelines for genetic testing for inherited cancer.
Check out the original article at: https://jamanetwork.com/journals/jama/article-abstract/2762602?resultClick=1