Gene: HOXB13

ICARE Newsletter Spring 2026

HOXB13 and Prostate Cancer

In a recently published study based on the VA’s Million Veteran Program, men with the HOXB13 p.G84E variant (the common variant in European populations, upon which much of the data is based) had a higher risk of prostate cancer, a slightly earlier age at diagnosis, and did not tend to develop more aggressive disease. Crawford, …

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Permanent link to this article: https://inheritedcancer.net/nfs20266/

ICARE Newsletter Spring 2026

NCCN Guidelines Insights Article

JNCCN released an article in the February issue with insights on: Prostate cancer screening: Pancreatic cancer screening: Testing for non-epithelial ovarian cancer: Cheng, et al. J Natl Compr Cancer Netw. 2026:24(2):2-10. PMID: 41671423.Article available at: https://jnccn.org/view/journals/jnccn/24/2/article-p2.xml. Social media post available at: https://www.facebook.com/share/p/1Rk6tvn2AB/

Permanent link to this article: https://inheritedcancer.net/nls20261/

ICARE Social Media Post November 2025

HOXB13 and Prostate Cancer

In a recently published study based on the VA’s Million Veteran Program, men with the HOXB13 p.G84E variant had: Learn more at: https://jnccn.org/view/journals/jnccn/23/10/article-e257055.xml Reference: Crawford et al. J Natl Compr Canc Netw. 2025;23(10):e257055. PMID: 40953603.

Permanent link to this article: https://inheritedcancer.net/post11252025/

ICARE Social Media Post October 2025

NCCN Guideline Update: HOXB13

The National Comprehensive Cancer Network (NCCN) released updated prostate cancer guideline for HOXB13 in the new Genetic/Familial High-Risk Assessment: Breast, Ovarian, Pancreatic, and Prostate Cancer guidelines (Version 2.2026) published today! Check out the full guidelines by creating a FREE account at:https://www.nccn.org/professionals/physician_gls/pdf/genetics_bopp.pdf

Permanent link to this article: https://inheritedcancer.net/post10102025-2/