CDH1 gastric cancer risk management options are included in the recently released National Comprehensive Cancer Network (NCCN) Genetic Familial High-Risk Assessment Colorectal, Endometrial, and Gastric Cancer guidelines.
Gastric (stomach) cancer risk management options include ⤸
- Gastrectomy (complete removal of the stomach) VERSUS screening through endoscopy
- Shared decision-making is recommended to discuss and decide upon cancer risk management options
In certain circumstances, gastrectomy is recommended based on findings at biopsy or endoscopy or other persistent unexplained symptoms. Regardless, a baseline endoscopy should be done before total gastrectomy.
CDH1 carriers who decide NOT to have a preventive gastrectomy should be offered screening every 6-12 months by upper endoscopy with multiple random biopsies.
Learn more by reading the full guidelines by creating a FREE account at:
https://www.nccn.org/professionals/physician_gls/pdf/genetics_ceg.pdf