A recent study showed that among men at highest risk for prostate cancer based on Polygenic Risk Score (PRS), more were found to have clinically significant disease (i.e., Gleason 7 or higher) than would have been found with PSA or MRI. In nearly 6,400 men who had PRS calculated:➡️ 745 (11.7%) had PRS in 90th …
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Estimating Polygenetic Risk Scores in non-Europeans through extrapolating from data in European descent populations is not accurate! Diversity in genomic studies is critically needed for both equity and scientific discovery. For more information, read the Genetics in Medicine editorial by ICARE Founder, Dr. Tuya Pal, here 👇https://www.gimjournal.org/article/S1098-3600(21)05396-X/fulltextReference: Pal. Genet Med. 2021 Nov 20;S1098-3600(21)05396-X. PMID: 34906472.
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