In January 2024, the American Society of Clinical Oncology (ASCO) in conjunction with the Society of Surgical Oncology released new guidelines for germline testing in patients with breast cancer, which include the following: For a full list of recommendations in this guideline, the article is available at: https://ascopubs.org/doi/10.1200/JCO.23.02225 Bedrosian, et al. J Clin Oncol. 2024;42(5):584-604. PMID:38175972. Social …
Tag: Risk Assessment
Permanent link to this article: https://inheritedcancer.net/icare-newsletter-spring-2024-new-guidelines-released-through-asco-society-of-oncology-germline-testing-in-patients-with-breast-center/
ICARE Social Media Post August 2021
Genetic Risk Assessment for Hereditary Renal Cell Carcinoma
ICARE Social Media Post August 2021
Genetic Risk Assessment for Hereditary Renal Cell Carcinoma
To view the 30 consensus statements, read the full article at: https://acsjournals.onlinelibrary.wiley.com/doi/10.1002/cncr.33679
Permanent link to this article: https://inheritedcancer.net/post83121/
ICARE Social Media Post August 2021
Breast Cancer Risk Among Breast Cancer Gene Carriers Varies by Polygenic Risk Score
ICARE Social Media Post August 2021
Breast Cancer Risk Among Breast Cancer Gene Carriers Varies by Polygenic Risk Score
For more information, read the ๐๐ฐ๐ถ๐ณ๐ฏ๐ข๐ญ ๐ฐ๐ง ๐๐ญ๐ช๐ฏ๐ช๐ค๐ข๐ญ ๐๐ฏ๐ค๐ฐ๐ญ๐ฐ๐จ๐บ article at the link below:https://ascopubs.org/doi/figure/10.1200/JCO.20.01992
Permanent link to this article: https://inheritedcancer.net/post81321/
ICARE Social Media Post April 2021
Komen Disparities Resource
ICARE Social Media Post April 2021
Komen Disparities Resource
Check out Susan G. Komen’s “๐๐ป๐ผ๐ ๐ฌ๐ผ๐๐ฟ ๐๐ถ๐๐๐ผ๐ฟ๐, ๐๐ป๐ผ๐ ๐ฌ๐ผ๐๐ฟ ๐ฅ๐ถ๐๐ธ” resource, which outlines disparities in breast cancer, how to understand your risk, and recommended screening and management practices. To learn more, please visit: ๐ https://www.komen.org/about-komen/our-impact/breast-cancer/health-equities-initiative/know-your-history/ ๐ https://blog.komen.org/news/black-history-month/
Permanent link to this article: https://inheritedcancer.net/post42021/
ICARE Social Media Post March 2021
Colorectal Cancer Risk Assessment Tool
ICARE Social Media Post March 2021
Colorectal Cancer Risk Assessment Tool
In honor of ๐๐ผ๐น๐ผ๐ฟ๐ฒ๐ฐ๐๐ฎ๐น ๐๐ฎ๐ป๐ฐ๐ฒ๐ฟ ๐๐๐ฎ๐ฟ๐ฒ๐ป๐ฒ๐๐ ๐ ๐ผ๐ป๐๐ต, we wanted to highlight the National Cancer Institute’s Colorectal Cancer Risk Assessment Tool (CCRAT) designed for healthcare providers to use with select patients to estimate the risk of colorectal cancer. You may access the tool at https://ccrisktool.cancer.gov
Permanent link to this article: https://inheritedcancer.net/post31221/
ICARE Social Media Post February 2021
Strategies to Enhance the Identification of Hereditary Breast Cancer Gene Carriers
ICARE Social Media Post February 2021
Strategies to Enhance the Identification of Hereditary Breast Cancer Gene Carriers
Check out a recent review article led by the ICARE team, published in ๐๐น๐ฑ๐ฆ๐ณ๐ต ๐๐ฆ๐ท๐ช๐ฆ๐ธ ๐ฐ๐ง ๐๐ฐ๐ญ๐ฆ๐ค๐ถ๐ญ๐ข๐ณ ๐๐ช๐ข๐จ๐ฏ๐ฐ๐ด๐ต๐ช๐ค๐ด, outlining strategies to improve the identification of inherited breast cancer gene carriers. Check out the full article at: https://www.tandfonline.com/doi/pdf/10.1080/14737159.2020.1816829?needAccess=true
Permanent link to this article: https://inheritedcancer.net/post20221/
ICARE Social Media Post December 2020
CDH1 Cancer Risks
ICARE Social Media Post December 2020
CDH1 Cancer Risks
When a ๐พ๐ฟ๐1 mutation is identified, several factors should be considered to figure out what the cancer risks might be and what medical management should be advised. Specifically, differences in cancer risks among those with a ๐พ๐ฟ๐1 mutation are not well understood. Identifying a ๐พ๐ฟ๐1 mutation in families with hereditary diffuse gastric cancer (HDGC) …
Permanent link to this article: https://inheritedcancer.net/post121520/
ICARE Social Media Post December 2020
Breast Cancer Polygenic Risk Score May Help Predict Risk of Contralateral Disease
ICARE Social Media Post December 2020
Breast Cancer Polygenic Risk Score May Help Predict Risk of Contralateral Disease
For further information, view the article available at: https://www.sciencedirect.com/…/pii/S0002929720303219
Permanent link to this article: https://inheritedcancer.net/post120120/
ICARE Social Media Post November 2020
Polygenic Risk Scores in Predicting Breast Cancer Risk
ICARE Social Media Post November 2020
Polygenic Risk Scores in Predicting Breast Cancer Risk
For further information, view the article available at: https://ascopubs.org/doi/full/10.1200/PO.19.00360
Permanent link to this article: https://inheritedcancer.net/post111320/
ICARE Social Media Post October 2020
Polygenic Risk Scores in Refining Breast Cancer Risks
ICARE Social Media Post October 2020
Polygenic Risk Scores in Refining Breast Cancer Risks
For further information, view the article available at: https://jamanetwork.com/journals/jamanetworkopen/fullarticle/2767768
Permanent link to this article: https://inheritedcancer.net/post102720/
ICARE Social Media Post March 2020
Polygenic Risk Score and Colon Cancer Risk
ICARE Social Media Post March 2020
Polygenic Risk Score and Colon Cancer Risk
A Polygenic Risk Score (PRS) is calculated using genetic differences throughout someoneโs DNA, in combination with clinical and family history of cancer. This score, alongside environmental and lifestyle risk factors, may help to identify people who might benefit from screening at an earlier age. Important facts about PRS: – It does NOT look for changes …
Permanent link to this article: https://inheritedcancer.net/post31320/
ICARE Newsletter Winter 2019
New Online Risk Calculator to More Accurately Predict Breast Cancer Risk
ICARE Newsletter Winter 2019
New Online Risk Calculator to More Accurately Predict Breast Cancer Risk
Prediction of breast cancer risk is important to identify those at highest and lowest risks, to help guide screening. A previously developed risk algorithm called Breast and Ovarian Analysis of Disease Incidence and Carrier Estimation Algorithm (BOADICEA) was recently extended to include truncating mutations in the BRCA genes, PALB2, CHEK2, and ATM. This online risk …
Permanent link to this article: https://inheritedcancer.net/11nlw2019/
ICARE Newsletter Summer 2017
Breast and Ovarian Cancer Risks Among BRCA Carriers Followed Over Time
ICARE Newsletter Summer 2017
Breast and Ovarian Cancer Risks Among BRCA Carriers Followed Over Time
Findings from an international study of over 6000 women with a BRCA1 mutation and almost 4000 women with a BRCA2 mutation followed for an average of 5 years were recently published.1 Results showed the risk of breast cancer by age 80 was ~70% for both BRCA1 and BRCA2 carriers. Rates of breast cancer increased until …
Permanent link to this article: https://inheritedcancer.net/1nls2017/
ICARE Newsletter Winter 2016
What Is the Risk for Ovarian Cancer Among Women with Mutations in Newer Ovarian Cancer Genes?
ICARE Newsletter Winter 2016
What Is the Risk for Ovarian Cancer Among Women with Mutations in Newer Ovarian Cancer Genes?
The most common form of inherited ovarian cancer is due to mutations in the BRCA1 and BRCA2 genes, which are present in 10-15% of women with ovarian cancer and lead to an ovarian cancer risk of up to 44% and 27%, respectively. Another set of genes known to raise ovarian cancer risks are the mismatch …
Permanent link to this article: https://inheritedcancer.net/2nlw2016/
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