Genetic/Familial High-Risk Assessment: Breast, Ovarian, and Pancreatic Cancer – Released September 11th, 2024 (V1.2025) Check out the full guidelines by creating a FREE account at www.nccn.org/professionals/physician_gls/pdf/genetics_bop.pdf Testing Updates: Gene Updates: Genetic/Familial High-Risk Assessment: Colorectal, Endometrial, and Gastric Cancer – Released August 8th, 2024 (V1.2024) Check out the full guidelines by creating a FREE account at …
Cancer Type: Endometrial Cancer
Permanent link to this article: https://inheritedcancer.net/icare-newsletter-fall-2024-national-comprehensive-cancer-network-nccn-guideline-updates/
ICARE Social Media Post September 2024
NCCN Colorectal, Endometrial, and Gastric Cancer Guidelines Update – VERSION 3
ICARE Social Media Post September 2024
NCCN Colorectal, Endometrial, and Gastric Cancer Guidelines Update – VERSION 3
The National Comprehensive Cancer Network (NCCN) released the new Genetic/Familial High-Risk Assessment Colorectal, Endometrial, and Gastric Cancer guidelines on August 8th, 2024. Updates include gynecologic risk and preventive surgery considerations for MLH1, MSH6, MSH2, and PMS2 carriers. You can check out the full guidelines by creating a FREE account at:https://www.nccn.org/professionals/physician_gls/pdf/genetics_ceg.pdf
Permanent link to this article: https://inheritedcancer.net/post91824/
ICARE Social Media Post September 2024
NCCN Colorectal, Endometrial, and Gastric Cancer Guidelines Update – VERSION 2
ICARE Social Media Post September 2024
NCCN Colorectal, Endometrial, and Gastric Cancer Guidelines Update – VERSION 2
The National Comprehensive Cancer Network (NCCN) released the new Genetic/Familial High-Risk Assessment Colorectal, Endometrial, and Gastric Cancer guidelines on August 8th, 2024. Updates include ⤸ You can check out the full guidelines by creating a FREE account at:https://www.nccn.org/professionals/physician_gls/pdf/genetics_ceg.pdf
Permanent link to this article: https://inheritedcancer.net/post91424/
ICARE Social Media Post September 2024
NCCN Colorectal, Endometrial, and Gastric Cancer Guidelines Update
ICARE Social Media Post September 2024
NCCN Colorectal, Endometrial, and Gastric Cancer Guidelines Update
The National Comprehensive Cancer Network (NCCN) released the new Genetic Familial High-Risk Assessment Colorectal, Endometrial, and Gastric Cancer guidelines on August 8th, 2024. Updates include ⤸• Endometrial cancer recommendations included throughout• Hereditary Diffuse Gastric Cancer section added (HGAST-1)• Gynecologic risk and preventive surgery considerations for those with Lynch Syndrome• Use of hormone replacement treatment following …
Permanent link to this article: https://inheritedcancer.net/post90324/
ICARE Social Media Post June 2023
Inherited Gene Mutation in Those with Multiple Primary Cancers
ICARE Social Media Post June 2023
Inherited Gene Mutation in Those with Multiple Primary Cancers
Among patients with multiple primary cancers, the proportion with inherited cancer gene mutations increased with the number of primary cancers:• 2 cancers: 13.1%• 3 cancers: 15.9%• 4+ cancers: 18.0% Many of the double primaries, such as those of the breast, ovary, colorectum, and endometrium, occurred in women who would already be eligible for genetic testing. …
Permanent link to this article: https://inheritedcancer.net/post60723/
ICARE Social Media Post May 2023
Lynch Syndrome: Skin Neoplasms
ICARE Social Media Post May 2023
Lynch Syndrome: Skin Neoplasms
According to a recent study among individuals with Lynch Syndrome: Use the link in bio to learn more! Reference: Zhong et al. J Am Acad Dermatol. 2023;S0190-9622(23)00173-1. PMID: 36773823.
Permanent link to this article: https://inheritedcancer.net/post50623/
ICARE Social Media Post March 2023
New Model: To identify those at high risk for Endometrial (Uterine) Cancer
ICARE Social Media Post March 2023
New Model: To identify those at high risk for Endometrial (Uterine) Cancer
Did you know endometrial cancer is the 4th most common cancer among females? Currently, clinical practice guidelines do not recommend endometrial cancer screening in the general population. A new risk prediction model was recently developed to identify those at high risk for endometrial (uterine) cancer to determine who could benefit from cancer screenings and risk-reducing …
Permanent link to this article: https://inheritedcancer.net/post32623/
ICARE Newsletter Spring 2022
BRCA1/2 Oral Contraceptives and Breast Cancer
ICARE Newsletter Spring 2022
BRCA1/2 Oral Contraceptives and Breast Cancer
A new study found that among BRCA1/2 carriers, oral contraceptive use strongly lowered cancer risk over one’s lifetime, even though at first, they raise risks of breast, ovarian, and endometrial cancer.Schrijver et al. J Natl Cancer Inst. 2022 Jan. PMID: 35048954. Social media post February 15th, 2022. Available at:https://tinyurl.com/post21522.
Permanent link to this article: https://inheritedcancer.net/icare-newsletter-spring-2022-brca1-2-oral-contraceptives-and-breast-cancer/
ICARE Social Media Post February 2022
BRCA1/2 Cancer Risks: Oral Contraceptives
ICARE Social Media Post February 2022
BRCA1/2 Cancer Risks: Oral Contraceptives
A new study found that among BRCA1/2 carriers oral contraceptive use strongly decreases lifetime cancer risk, despite an 𝗶𝗻𝗶𝘁𝗶𝗮𝗹 increase in breast, ovarian, and endometrial cancer risk. Read the full article to learn more!https://pubmed.ncbi.nlm.nih.gov/35048954/Reference: Schrijver et al. J Natl Cancer Inst. 2022 Jan 20;djac004. PMID: 35048954
Permanent link to this article: https://inheritedcancer.net/post21522/
ICARE Newsletter Summer 2020
Treatment Advances Among Those with Lynch Syndrome
ICARE Newsletter Summer 2020
Treatment Advances Among Those with Lynch Syndrome
There continue to be ongoing advances in treatment studies among those with inherited cancer gene mutations, which are rapidly being followed by FDA approval for specific cancer treatments. Select studies and advances are summarized below: Lynch Syndrome: Colorectal Cancer: Among patients with MSI-H or MMR-deficient colorectal cancers (frequently seen among those with Lynch syndrome), pembrolizumab …
Permanent link to this article: https://inheritedcancer.net/7nls2020/
ICARE Social Media Post January 2020
Advances in Treatment for Lynch Syndrome-Related Endometrial Cancer
ICARE Social Media Post January 2020
Advances in Treatment for Lynch Syndrome-Related Endometrial Cancer
A recent phase II study showed increased response to an immunotherapy drug (avelumab), in women with endometrial cancer with mismatch repair deficiency. Among women with Lynch Syndrome, the risk for endometrial cancer (which often has mismatch repair deficiency) is raised. This new study shows promising treatment options for women with endometrial cancer and Lynch syndrome …
Permanent link to this article: https://inheritedcancer.net/13020/
ICARE Newsletter Summer 2018
Refining Cancer Risks Among Individuals with Lynch Syndrome
ICARE Newsletter Summer 2018
Refining Cancer Risks Among Individuals with Lynch Syndrome
Over the past year, multiple studies have refined risks and types of cancer among individuals with Lynch syndrome. Through a Scandinavian study, risks for 13 types of cancer (with colorectal cancers being excluded), were reported to be elevated with differences related to gender, age, and the gene in which mutation was present. Incidence rates of …
Permanent link to this article: https://inheritedcancer.net/5nls2018/
ICARE Newsletter Summer 2016
What Are the Endometrial Cancer Risks Among BRCA Carriers?
ICARE Newsletter Summer 2016
What Are the Endometrial Cancer Risks Among BRCA Carriers?
Although BRCA mutations confer increased risk for ovarian, fallopian tube, and primary peritoneal cancer, there have been limited and conflicting risks reported for endometrial cancer. Consequently, current practice guidelines only recommend the removal of the fallopian tubes and ovaries as a risk-reducing option for BRCA carriers.1 Specifically, through a prospective study of 4500 women with …
Permanent link to this article: https://inheritedcancer.net/9nls2016/
ICARE Newsletter Summer 2016
Risk of Second Cancers Among Those with PTEN Mutations
ICARE Newsletter Summer 2016
Risk of Second Cancers Among Those with PTEN Mutations
A recently published study to evaluate the risk of second cancers among PTEN mutation carriers showed that women with breast cancer had a 10-year second breast cancer cumulative risk of almost 30%. Overall, the risk of second primary cancers was almost 8-fold that of the general population, primarily due to the higher risks of cancer …
Permanent link to this article: https://inheritedcancer.net/8nls2016/
ICARE Newsletter Summer 2014
Ask the Expert
ICARE Newsletter Summer 2014
Ask the Expert
The following question was addressed by Dr. Steven Narod who is a Tier I Canada Research Chair in Breast Cancer and a senior scientist at Women’s College Research Institute in Toronto, Canada. Dr. Narod is a world-leader in the field of breast and ovarian cancer genetics. Over the course of his career, he has profoundly shaped …
Permanent link to this article: https://inheritedcancer.net/5nls2014/
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